Next-Generation Insights with Evosep™ Eno
Unlock the full potential of LC-MS proteomics with a complete, integrated solution — not just individual components.
Evosep™ Eno redefines how proteomics workflows are built by combining standardized, high-throughput sample preparation with robust LC-MS performance. It’s not just fast — it’s designed for real-world productivity, ensuring sensitivity, reliability, and consistency at every step.
Why Evosep Eno?
Maximum Reliability
Start strong and stay running. Evosep Eno delivers near 100% uptime with minimal setup — optimized for continuous, out-of-the-box productivity.
Cost-Efficient by Design
Reduce your cost-per-sample by up to 64%, while increasing MS utilization by 29% — delivering more data, faster, for less.
Patented Innovation
Built on proprietary sample introduction and separation technologies (EP3519808B1, EP3519807B1, US12298284B) — offering seamless integration and superior performance across the entire workflow.
Versatility Through Standardised Methods
- Evosep Eno uses optimized methods with specified columns for out-of-the-box performance.
- Standardized workflows simplify application support and reduce variability.
- Low overhead time ensures maximum utilization of the mass spectrometer.
Effortless To Learn,
Easy To Use
- Each standardized method includes a detailed description and expected performance metrics.
- Instantly achieve expert-level results with step-by-step method guidance.
- Follow listed column and emitter specifications to confirm reproducibility.
- Support your setup using individual method application notes for reliable outcomes.
Revolutionizing Sample Handling
Evotip Pure is a precision technology device with extremely high efficiency, integrating desalting with LC-MS sample introduction.
Sustainable Scalable Workflows
- Evotip miniaturizes workflows by requiring only enough sample for a single injection.
- Reduces sample prep waste for a more sustainable and cost-efficient process.
- Enables fully automated sample loading protocols for seamless operation.
- Allows immediate sample clean-up and efficient storage for analysis readiness.
Whisper Zoom sets a new standard
Whisper Zoom delivers sensitivity for highly versatile applications. Robust methods enable high-throughput analysis for inter-laboratory studies, while a short learning curve facilitates rapid method adaptation.
Robust High Sensitivity Workflows
- Whisper Zoom methods deliver cutting-edge performance for advanced proteomics.
- Designed to meet growing demands for scalability, robustness, and ease of use.
- Tailored for standardized, high-sensitivity workflows with minimal variability.
- Utilizes Evotip Pure for sensitive storage and efficient LC-MS sample introduction.
Seamless integration
The Evosep Eno connects easily with leading mass spectrometers using optimized emitters and zero dead-volume connectors. Control is provided by integrated software drivers.
Application Notes
New Standards with Evosep Eno
- Sets a new benchmark in LC-MS-based proteomics with unmatched chromatographic performance.
- Delivers robust reproducibility and precision across laboratories.
- Supports throughput from 30 to 500 samples per day to meet diverse study demands.
- Offers up to 80% better retention time reproducibility and sharper peaks.
- Improves quantification and overall sensitivity for both targeted and discovery workflows.
Multi-Laboratory Study of Evosep Eno
- Demonstrates consistent performance across multiple laboratories and instrument platforms.
- Validates reproducibility in diverse sample preparation protocols.
- Delivers high sensitivity and low variability across all sites.
- Supports standardized proteomics with confidence in collaborative environments.
- Minimizes setup variation for streamlined multi-site research.
Throughput and Depth with Eno Standard Methods
- Offers a standardized method portfolio supporting up to 500 samples per day.
- Balances high throughput with deep proteome coverage.
- Delivers reproducible chromatography and excellent peak shapes.
- Scales from routine screening to advanced discovery workflows.
- Maximizes MS efficiency without compromising data quality.
Scalable End-to-End Proteomics Workflows
- Enables fully automated, end-to-end proteomics workflows using Evosep Eno.
- Demonstrates the ability to process over 1,000 samples in under three days.
- Combines streamlined digestion, Evotip loading, and LC-MS analysis.
- Delivers high-throughput performance with reliable, reproducible results.
- Drives cost-efficiency while scaling for large-volume studies.
Evotip Pure in High-Sensitivity LC-MS Workflows
- Streamlines high-sensitivity LC-MS workflows by minimizing sample loss and carryover.
- Reduces storage complexity with a disposable trap-column design.
- Enables reproducible analysis of ultra-low input samples, ideal for single-cell proteomics.
- Ensures consistent recovery and long-term stability.
- Fully compatible with automation for scalable proteomic sample prep.
Targeted Plasma Proteomics with Eno
- Delivers scalable targeted LC-MS workflows with ultra-low detection limits.
- Provides excellent retention time stability for confident quantification.
- Designed for plasma biomarker analysis and high-precision assays.
- Integrates automated sample preparation with scheduled MRM workflows.
- Ensures accuracy, sensitivity, and throughput — even at amol levels.
Evosep ENO Brochure
- Fully integrated solution combining sample preparation with LC-MS analysis.
- Supports throughput from 30 to 500 samples/day using standardized methods.
- Engineered for robustness and near 100% uptime with minimal user intervention.
- Significantly reduces cost-per-sample while increasing MS utilization efficiency.
- Leverages patented sample introduction and separation technologies.
- Delivers reproducible, high-quality data across labs and applications.